The Journal of Organic Chemistry

Diels-Alder reactions of 1, 2, 4-triazines. Synthesis of thieno [2, 3-c] pyridines and 3, 4-dihydro-2H-thiopyrano [2, 3-c] pyridines from 6-(alkynylthio)-1, 2, 4-triazines

EC Taylor, JE Macor

Index: Taylor, Edward C.; Macor, John E. Journal of Organic Chemistry, 1989 , vol. 54, # 21 p. 4984 - 4989

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Citation Number: 13

Abstract

0022-3263/89/1954-4984 $01.50/0 venient synthesis of 1, 2, 4-triazin-6-ones4 and their corresponding 6-thi0nes.~~ Alkylation of the latter with 4-halo-1-butynes and 5-hdo-l- pentynes, utilizing procedures analogous to those previously employed for the preparation of 3-(alkynylthi0)-1, 2, 4-triazines,~~ provides a family of tethered diene-dienophile pairs that are attractive intermediates for the preparation of thieno [2, 3-c] pyridines and 3, 4-dihydro- ...