Direct Trifluoromethylthiolation of Alcohols under Mild Reaction Conditions: Conversion of R OH into R SCF3

P Nikolaienko, R Pluta…

Index: Pluta, Roman; Nikolaienko, Pavlo; Rueping, Magnus Angewandte Chemie - International Edition, 2014 , vol. 53, # 6 p. 1650 - 1653 Angew. Chem., 2014 , vol. 126, # 6 p. 1676 - 1679,4

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Citation Number: 26

Abstract

Abstract A direct process for the trifluoromethylthiolation of allylic and benzylic alcohols under mild conditions has been developed. A wide range of free alcohols underwent nucleophilic substitution in the presence of stable CuSCF 3 and BF 3⋅ Et 2 O to give the