Highly Enantioselective Synthesis of N??Protected β??Amino Malonates Catalyzed by Magnetically Separable Heterogeneous Rosin??Derived Amino Thiourea Catalysts …

…, X Jiang, X Li, C Hou, Y Jiang, K Hou, R Wang…

Index: Zhu, Hao; Jiang, Xianxing; Li, Xinghua; Hou, Chen; Jiang, Yu; Hou, Ke; Wang, Rui; Li, Yanfeng ChemCatChem, 2013 , vol. 5, # 8 p. 2187 - 2190

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Citation Number: 5

Abstract

The Mannich reaction is one of the most versatile and attractive methods for the construction of nitrogen-containing compounds in organic synthesis.[1] In particular, β-amino-carbonyl derivatives constitute a class of compounds that can be readily converted into valuable synthetic building blocks or biologically active molecules.[2] Optically active β-amino acids have been found both in a series of biologically active natural peptides and as an ...

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