2, 4-Dichloro-5-(1-o-carboranylmethyl)-6-methylpyrimidine: a potential synthon for 5-(1-o-carboranylmethyl) pyrimidines

RC Reynolds, TW Trask…

Index: Reynolds, Robert C.; Trask, Todd W.; Sedwick, W. David Journal of Organic Chemistry, 1991 , vol. 56, # 7 p. 2391 - 2395

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Citation Number: 17

Abstract

A number of approaches to the synthesis of 5-(1-0-carboranylmethy1)-substituted pyrimidines are described including the successful synthesis of 2, 4-dichloro-5-(lo- carboranylmethyl)-6-methylpyrimidine. This general approach could potentially be utilized to produce a variety of boron-containing pyrimidine analogues (0-carboranes and/or nido- undecaborates). This class of compounds is of special interest because of recent ...