Effect of organic compounds on reproductive processes. I. Alkylating agents from octamethylenediamine and various xylylenediamines

WA Skinner, HC Tong, TE Shellenberger…

Index: Skinner,W.A. et al. Journal of Medicinal Chemistry, 1965 , vol. 8, p. 647 - 650

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Citation Number: 5

Abstract

Alkylating agents derived from m-and p-xylylenediamine and from octamethylenedianiine were synthesized and evaluated for their effects on the reprodnrtive processes of the housefly (Jfirsca domesttca L.) and the Japanese quail (Coturnzz coturniz japonica). Some of the aziridinyl derivatives rere found to interfere with reproduction of the housefly. h better understanding of the relationship between the chemical structure of organic compounds ...