Synthesis of trisubstituted isoxazoles via in situ trapping strategy from α-nitro carbonyl compounds and methyl ketones or terminal aryl alkenes
Y Yang, M Gao, C Deng, DX Zhang, LM Wu, WM Shu…
Index: Yang, Yan; Gao, Meng; Deng, Cong; Zhang, Dong-Xue; Wu, Liu-Ming; Shu, Wen-Ming; Wu, An-Xin Tetrahedron, 2012 , vol. 68, # 31 p. 6257 - 6262
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Citation Number: 15
Abstract
A highly efficient domino method for the synthesis of trisubstituted isoxazoles has been established from α-nitro carbonyl compounds and methyl ketones or terminal aryl alkenes. Simple and readily available starting materials, mild reaction conditions and very simple operation are significant advantages of the reaction.
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