Synthesis and capillary electrophoretic analysis of enantiomerically enriched reference standards of MDMA and its main metabolites

…, R De la Torre, M Farré, J Segura, A Llebaria…

Index: Pizarro, Nieves; De la Torre, Rafael; Farre, Magi; Segura, Jordi; Llebaria, Amadeu; Joglar, Jesus Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 4 p. 1085 - 1092

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Citation Number: 27

Abstract

Enantiomerically-enriched (S)-3, 4-methylenedioxymethamphetamine (MDMA) and its main metabolites (S)-4-hydroxy-3-methoxymethamphetamine (HMMA) and (S)-3, 4- dihydroxymethamphetamine (HHMA) were prepared for unequivocal identification of the differential enantioselective metabolism of these compounds as well as for its application in the analysis of biological samples. Capillary electrophoresis with cyclodextrin derivatives ...