Copper-Catalyzed Oxidative Coupling of 2, 4, 6-Trimethylphenol with Oxygen.

K Oyaizu, K Saito, E Tsuchida

Index: Oyaizu, Kenichi; Saito, Kei; Tsuchida, Eishun Chemistry Letters, 2000 , # 11 p. 1318 - 1319

Full Text: HTML

Citation Number: 12

Abstract

The outcome of the copper-catalyzed oxidation of 2,4,6- trimethylphenol with oxygen has been dominated by oxygenat- ed products such as 4-hydroxy-3,5-dimethylbenzaldehyde, 2,6- dimethyl-p-benzoquinone, and 4-alkoxy-2,6-dimethylphe- nols.1,2 This reaction, effectively catalyzed by copper(II) chlo- rides coupled with diethylamine, hydroxylamine, or oximes, has attracted much attention not only as a convenient synthetic method for p-hydroxybenzaldehyde that is an ...