In situ generation of hydroperoxide by oxidation of benzhydrols to benzophenones using sodium hydride under oxygen atmosphere: use for the oxidative cleavage of …

S Kang, S Lee, M Jeon, SM Kim, YS Kim, H Han…

Index: Kang, Sunhae; Lee, Soyoung; Jeon, Minju; Kim, Sun Min; Kim, Young Sug; Han, Hogyu; Yang, Jung Woon Tetrahedron Letters, 2013 , vol. 54, # 5 p. 373 - 376

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Citation Number: 3

Abstract

A facile oxidative cleavage of cyclic 1, 2-diketones 1 to dicarboxylic acids 3 with hydroperoxide generated in situ has been developed. In situ generation of hydroperoxide was effected by the oxidation of 4, 4′-dichlorobenzhydrol 2f to 4, 4′- dichlorobenzophenone 4f using sodium hydride under oxygen atmosphere.

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