Tetrahedron Letters

Tuning the solubility of hepta (p-benzamide) s via the monomer sequence

H Seyler, A Kilbinger

Index: Seyler, Helga; Kilbinger, Andreas Tetrahedron Letters, 2013 , vol. 54, # 8 p. 753 - 756

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Citation Number: 3

Abstract

The automated synthesis of hepta (p-benzamide) heterosequences on solid support using a modified peptide synthesizer is reported. The oligomers are synthesized from 4- aminobenzoic acid and 4-amino-2-(hexyloxy) benzoic acid, the latter carrying a solubilizing hexyl side chain. It is known from previous studies that both the unsubstituted hepta (p- benzamide) and the fully hexyloxy-substituted hepta (p-benzamide) are insoluble in all ...