Preparation of New tert-Butyl Substituted Coumarins, Thiocoumarins and Dithiocoumarins

J Voss, R Edler, G Adiwidjaja

Index: Voss, Jrgen; Edler, Ronald; Adiwidjaja, Gunadi Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 8 p. 1893 - 1905

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Citation Number: 3

Abstract

6-tert-Butyl-4-methyl-and 6, 8-di-tert-butyl-4-methylcoumarin were prepared from tert- butylphenols and diketene via the corresponding aryl acetoacetates. 6-tert-Butyl-4-methyl- thiocoumarin (6) was obtained from 6-tert-butylthiophenol. Thionation with Lawesson's or davy's reagent led to the related thion-and dithiocoumarins. The structures were proved by nmr spectroscopy and an x-ray structure analysis of 6.