PIPERIDINE DERIVATIVES. XI. 3-CARBETHOXY-4-PIPERIDONE AND 4-PIPERIDONE HYDROCHLORIDE

GM Kuettel, SM McElvain

Index: Kuettel; McElvain Journal of the American Chemical Society, 1931 , vol. 53, p. 2692,2696

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Citation Number: 7

Abstract

In an effort to prepare 4-piperidone1 Ruzicka and Fornasir'carried out an internal acetoacetic ester condensation of P,, B'-dicarbethoxydiethyl-amine. No attempt was made to isolate the intermediate 3-carbethoxy-4-piperidone. The reaction mixture containing this latter compound was subjected directly to reaction conditions which would bring about its hydrolysis and decarboxylation. The resulting 4-piperidone was not obtained in the form of ...