p-Toluenesulfonylacetylene as thiol protecting group
…, F Iradier, R Medel, J Plumet
Index: Arjona, Odon; Iradier, Fatima; Medel, Rocio; Plumet, Joaquin Journal of Organic Chemistry, 1999 , vol. 64, # 16 p. 6090 - 6093
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Citation Number: 27
Abstract
The protection of a thiol group constitutes a common problem in synthetic organic chemistry. 1 Among the methods so far described, those which make use of Michael addition reactions are very common. 2 However, all of them suffer some limitations derived from the use of basic conditions for the protection step or acidic, reductive, or basic conditions for the deprotection step. Phenyl vinyl sulfone and p-tolyl isobutenyl sulfone have been ...
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