The Journal of Organic Chemistry

Carboxylate protection for the synthesis of 4, 5-disubstituted 1-methylimidazoles

G Shapiro, B Gomez-Lor

Index: Journal of Organic Chemistry, , vol. 59, # 19 p. 5524 - 5526

Full Text: HTML

Citation Number: 28

Abstract

... (8) It has been shown that the dimethylamide ofN-methylimidazole- 2-carboxylic acid is readily deprotonated in the 5-position but the vigorous conditions of the amide hydrolysis-decarboxylation detract from this chemistry. Ngochindo, RIJ Chem. ... J. Org. Chem., Vol. 59, No. ...

Related Articles:

Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor α (TNF-α) production: Selectivity and in vivo antiinflammatory activity of novel 8- …

[Green, Neal; Hu, Yonghan; Janz, Kristin; Li, Huan-Qiu; Kaila, Neelu; Guler, Satenig; Thomason, Jennifer; Joseph-McCarthy, Diane; Tam, Steve Y.; Hotchandani, Rajeev; Wu, Junjun; Huang, Adrian; Wang, Qin; Leung, Louis; Pelker, Jefferey; Marusic, Suzana; Hsu, Sang; Telliez, Jean-Baptiste; Hall, J. Perry; Cuozzo, John W.; Lin, Lih-Ling Journal of Medicinal Chemistry, 2007 , vol. 50, # 19 p. 4728 - 4745]

(+)-Echinobetaine B: isolation, structure elucidation, synthesis and preliminary SAR studies on a new nematocidal betaine from a southern Australian marine sponge, …

[Organic and Biomolecular Chemistry, , vol. 3, # 1 p. 118 - 122]

More Articles...