Preparation of 5-(2-Methoxy-4-nitrophenyl) oxazole: A Key Intermediate for the Construction of VX-497
RJ Herr, DJ Fairfax, H Meckler…
Index: Organic Process Research and Development, , vol. 6, # 5 p. 677 - 681
Full Text: HTML
Citation Number: 18
Abstract
... from the acidic aqueous layer were examined (eg, extraction with other organic solvents, and ... After chromatographic purification, this procedure afforded the desired aryl aldehyde 8 as an orange ... Thus, this two-step process to provide 8 was achieved from commercially available ...
Related Articles:
[Herr, R. Jason; Fairfax, David J.; Meckler, Harold; Wilson, Jeffrey D. Organic Process Research and Development, 2002 , vol. 6, # 5 p. 677 - 681]
Novel amide-based inhibitors of inosine 5′-monophosphate dehydrogenase
[Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 20 p. 2879 - 2882]
Novel amide-based inhibitors of inosine 5′-monophosphate dehydrogenase
[Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 20 p. 2879 - 2882]