Syntheses of apogalanthamine analogues as. ALPHA.-adrenergic blocking agents. XII. Syntheses and stereochemistry of methoxy and methylenedioxy derivatives of …

木原勝, 大西邦義, /小林茂, S KOBAYASHI

Index: Kihara; Ohnishi; Vangveravong; Kobayashi Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 4 p. 870 - 876

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Abstract

8-Hydroxy-5, 6, 7, 8-tetrahydrodibenz [c, e] azocines 4b, c and their methoxy and methylenedioxy derivatives 7a-c and 8a-c were prepared by cyclization of O-protected 1- phenyl-2-aminoethanols 6b, c, 9a-c and 10a-c with zerovalent nickel, followed by hydrolysis

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