Facile Method for Solid??Phase Synthesis of Vinyl Sulfones Using Polystyrene??Supported Selenomethyl Aryl Sulfone

SR Sheng, W Zhou, MH Zhong, XL Liu…

Index: Sheng, Shou-Ri; Zhou, Wei; Zhong, Ming-Hua; Liu, Xiao-Ling; Chen, Hui-Zong Synthetic Communications, 2005 , vol. 35, # 6 p. 815 - 821

Full Text: HTML

Citation Number: 7

Abstract

Solid??phase synthesis has gained widespread acceptance in combinatorial chemistry related to drug discovery in order to accelerate lead generation and lead optimization.1 View all references Synthesis on a polymer support shows a number of advantages as compared to solution chemistry. The most salient one is the possibility of applying excesses of reagents and removing them without involving time??consuming separation techniques. Vinyl sulfones have now ...