Synthesis of peramine, an insect feeding deterrent mycotoxin from Acremonium lolii

MA Brimble, DD Rowan

Index: Brimble, Margaret A.; Rowan, Daryl R. Journal of the Chemical Society, Chemical Communications, 1988 ,  # 14  p. 978 - 979

Full Text: HTML

Citation Number: 15

Abstract

The first synthesis of peramine (l), the major insect feeding deterrent isolated from perennial ryegrass infected with the endophytic fungus Acremonium lolii, is reported. ... The alkaloid peramine (1), containing the novel 2-methyl- pyrrolo[ 1,2-u]pyrazin-l(2H)-one ring system together with a monosubstituted guanidino group, has recently been identi- fiedl as the principal insect feeding deterrent isolated from perennial ryegrass (Lolium perenne L.) infected with the ...