Tetrahedron

A convenient method for the preparation of α-vinylfurans by phosphine-initiated reactions of various substituted enynes bearing a carbonyl group with aldehydes

H Kuroda, E Hanaki, H Izawa, M Kano, H Itahashi

Index: Kuroda, Hirofumi; Hanaki, Emi; Izawa, Hironori; Kano, Michiko; Itahashi, Hiromi Tetrahedron, 2004 , vol. 60, # 8 p. 1913 - 1920

Full Text: HTML

Citation Number: 57

Abstract

α-Vinylfurans were obtained by phosphine-initiated cyclization of various enynes bearing a carbonyl group at the ene end in the presence of various aldehydes, in moderate to high yields. The reaction may consist of 1, 6-addition of phosphine to the enynes, ring closure, and Wittig reaction between the ylid resulting from cyclization and an aldehyde. Thus, various aldehydes were able to be used in the reaction. The reaction was influenced ...