Tetrahedron letters

A general highly efficient access to prenylated phenolic natural products. Synthesis of colletochlorins B and D

H Saimoto, T Hiyama

Index: Saimoto, Hiroyuki; Hiyama, Tamejiro Tetrahedron Letters, 1986 ,  vol. 27,  # 5  p. 597 - 600

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Citation Number: 19

Abstract

Abstract A general approach is reported for the synthesis of phenolic natural products having terpenoid side chains:(1) construction of the requisite bromophenol ethers,(2) coupling the aromatic ring with a terpenoid chain through copper (I) ate complex, and (3) ether cleavage under neutral or basic conditions, and the feasibility of this strategy is demonstrated by efficient synthesis of colletochlorins B and D.