Tetrahedron: Asymmetry

Stereoselective synthesis of homochiral alpha substituted o-methoxybenzyl alcohols via nucleophilic additions to kinetically resolved homochiral tricarbonyl (η 6-o- …

LA Bromley, SG Davies, CL Goodfellow

Index: Bromley, Lindsay A.; Davies, Stephen G.; Goodfellow, Craig L. Tetrahedron: Asymmetry, 1991 ,  vol. 2,  # 2  p. 139 - 156

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Citation Number: 73

Abstract

Abstract Tricarbonyl (η 6-o-anisaldehyde) chromium (0) has been kinetically resolved via the selective hydrolysis of one of theL-valinol derived imine presence of deactivated alumina. An X-ray crystal structure analysis on the adduct formed between L-valinol and homochiral (+)-tricarbonyl (η 6-o-anisaldehyde) chromium (0) unambiguously established the presence of the corresponding imine and not oxazolidine and confirmed the absolute configuration ...