Journal of Agricultural and Food Chemistry

Synthesis and herbicidal activity of phenylproparginols.

JJ Parlow, RD Clark

Index: Parlow, John J.; Clark, Robert D. Journal of Agricultural and Food Chemistry, 1994 , vol. 42, # 11 p. 2600 - 2609

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Citation Number: 9

Abstract

A three-steplone-pot procedure was developed for preparing herbicidal fluorophenylproparginols from acetophenones by way of an enol phosphate intermediate. Side-by-side testing of 16 of the more active analogs showed that trans-2-methyl-l-[2-(4- methoxy-2, 3, 5, 6-tetrafluorophenyl) ethynyll-cyclohexanol (2112) was the most potent example. On the basis of the biological response data obtained for these first-tier analogs, ...

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