Efficient synthesis of 3-hydroxy-1, 4-benzodiazepines oxazepam and lorazepam by new acetoxylation reaction of 3-position of 1, 4-benzodiazepine ring

I Cepanec, M Litvic, I Pogorelic

Index: Organic Process Research and Development, , vol. 10, # 6 p. 1192 - 1198

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Citation Number: 24

Abstract

... Organic Process Research & Development. ... However from the observation of this reaction we concluded that the process presumably includes the iodination of the ... the new syntheses of widely used anxiolytic drugs oxazepam (1) and lorazepam (2). The processes for lorazepam ...