Tetrahedron

Enzyme catalyzed monohydrolysis of 2-aryl-1 3-propanediol diacetates. A study of structural effects of the aryl moiety on the enantioselectivity

G Guanti, E Narisano, T Podgorski, S Thea, A Williams

Index: Guanti, Giuseppe; Narisano, Enrica; Podgorski, Tadeusz; Thea, Sergio; Williams, Andrew Tetrahedron, 1990 ,  vol. 46,  # 20  p. 7081 - 7092

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Citation Number: 60

Abstract

PPL catalyzed monohydrolysis of 2-aryl substituted 13-propanediol diacetates afforded the corresponding monoacetates in acceptable to fair chemical and optical yields. Electronic effects in the aromatic ring were examined. Elaboration of some 2-arylpropanediol monoacetates to optically active 2-arylpropanols and propanoic acids was performed.