Synthesis and comparison of some cardiovascular properties of the stereoisomers of labetalol

…, W Chang, M Cohen, T Baum, S Ehrreich…

Index: Gold, Elijah H.; Chang, Wei; Cohen, Marvin; Baum, Thomas; Ehrreich, Steward; et al. Journal of Medicinal Chemistry, 1982 ,  vol. 25,  # 11  p. 1363 - 1370

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Citation Number: 74

Abstract

20852.(3)(a) LHC Lunts and DT Collin, US. Patent 4012444 (1977);(b) JE Clifton, I. Collins, P. Hallett, D. Hartley, L. HC Lunts, and PD Wicks, J. Med. Chem., 25,670 (1982). This paper also describes the synthesis of the isomers.(4) For reviews of the animal pharmacology, see (a) DA Richards, J. Tuckman, and BNC Prichard, Br. J. Pharmacol., 3, 849 (1976);(b) RT Brittain and GP Levy, Br. J. Clin.