N-Phenyl-4-pyrazolo [1, 5-b] pyridazin-3-ylpyrimidin-2-amines as potent and selective inhibitors of glycogen synthase kinase 3 with good cellular efficacy

FX Tavares, JA Boucheron, SH Dickerson…

Index: Journal of Medicinal Chemistry, , vol. 47, # 19 p. 4716 - 4730

Full Text: HTML

Citation Number: 76

Abstract

... Journal of Medicinal ... Department of Medicinal Chemistry, Department of Metabolic Diseases, Department of Computational, Analytical and Structural Sciences ... 4730. DOI: 10.1021/jm040063i. Publication Date (Web): August 13, 2004. Copyright © 2004 American Chemical Society ...

Enantioselective synthesis of both enantiomers of various propargylic alcohols by use of two oxidoreductases

[Schubert, Thomas; Hummel, Werner; Kula, Maria-Regina; Mueller, Michael European Journal of Organic Chemistry, 2001 , # 22 p. 4181 - 4187]

Microstucture of Water Equilibrted with Organic Phase

[Liu, Jinxian; Xie, Xi; Ma, Shengming Synthesis, 2012 , vol. 44, # 10 p. 1569 - 1576]

Palladium-Catalyzed Cross-Coupling Syntheses of Benzotriazolyl Enynes and a General Route to Enynyl Ketones and Alkynyl Ketones

[Journal of Organic Chemistry, , vol. 62, # 23 p. 8201 - 8204]

Unexpected Elimination to α, β-Alkynylketones in the Reaction of Dianions of 1-Arylenaminones with Trimethylchlorosilane

[Tetrahedron Letters, , vol. 32, # 48 p. 7091 - 7092]

N-Phenyl-4-pyrazolo [1, 5-b] pyridazin-3-ylpyrimidin-2-amines as potent and selective inhibitors of glycogen synthase kinase 3 with good cellular efficacy

Abstract

Related Articles:

More Articles...