The Journal of Organic Chemistry

A cyclopentanone annulation via intramolecular acylation of alkylsilanes

H Urabe, I Kuwajima

Index: Urabe, Hirokazu; Kuwajima, Isao Journal of Organic Chemistry, 1984 , vol. 49, # 6 p. 1140 - 1141

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Citation Number: 13

Abstract

Sir: Cyclopentanones are widely found in naturally oc- curring products, and exploration of new procedures for construction of such frameworks from readily available acyclic precursors is still required in natural product synthesis. Among the many approaches, a ring closure by the combination of the acyl cation and the alkyl anion equivalent would be one of the most straightforward methodologies (Scheme I). To effect this transformation, the alkyl anion equivalent depicted in Scheme I ...