The First General, Highly Enantioselective Lewis Base Organo??catalyzed Hydrosilylation of Benzoxazinones and Quinoxalinones

ZY Xue, Y Jiang, XZ Peng, WC Yuan…

Index: Xue, Zhou-Yang; Jiang, Yan; Peng, Xiao-Zhi; Yuan, Wei-Cheng; Zhang, Xiao-Mei Advanced Synthesis and Catalysis, 2010 , vol. 352, # 13 p. 2132 - 2136

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Citation Number: 32

Abstract

Abstract The first general, highly enantioselective hydrosilylation of benzoxazinones and quinoxalinones has been developed. The chiral Lewis base organocatalysts that are readily accessible from (1S, 2R)-ephedrine and (1R, 2S)-ephedrine promoted the title reaction to afford various chiral dihydrobenzoxazinones and dihydroquinoxalinones with good yields as well as good enantioselectivities.

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