Tetrahedron

Oxidative transformations in the aporphine alkaloid series

MP Cava, A Venkateswarlu, M Srinivasan, DL Edie

Index: Cava,M.P. et al. Tetrahedron, 1972 , vol. 28, p. 4299 - 4307

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Citation Number: 33

Abstract

Oxidation of the non-phenolic aporphines nuciferine (1), dicentrine (3), ocopodine (4) and thalicarpine (7) by iodine affords the corresponding dehydroaporphines (2, 5, 6 and 8). In contrast. iodine oxidation of non-phenolic noraporphines proceeds all the way to the oxoaporphine stage: thus. O-methylnandigerine (9), nordicentrine (11) and ovigerine (12) yield the corresponding oxoaporphines (10, 13 and 14). The phenolic aporphine N- ...