Pd catalyzed coupling of 1, 2-dibromoarenes and anilines: formation of N, N-diaryl-o-phenylenediamines

T Wenderski, KM Light, D Ogrin, SG Bott, CJ Harlan

Index: Wenderski, Todd; Light, Kenneth M.; Ogrin, Doug; Bott, Simon G.; Harlan, C. Jeff Tetrahedron Letters, 2004 , vol. 45, # 37 p. 6851 - 6853

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Citation Number: 52

Abstract

1, 2-Dibromoarenes were coupled with aniline derivatives to yield N, N-diaryl-o- phenylenediamines in moderate to good yield using a palladium/phosphine or palladium/carbene catalyst system. Under similar conditions, 1, 2, 4, 5-tetrabromobenzene was coupled with aniline derivatives to produce the corresponding tetrasubstituted derivatives which are oxidized on workup to yield azophenines. The sequential reaction of ...