Guest binding and orientation within open nanoscale hosts

ZR Laughrey, CLD Gibb, T Senechal…

Index: Laughrey, Zachary R.; Gibb, Corinne L. D.; Senechal, Tangi; Gibb, Bruce C. Chemistry - A European Journal, 2003 , vol. 9, # 1 p. 130 - 139

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Citation Number: 61

Abstract

Abstract The synthesis of three different nanoscale molecular hosts is reported. These cavitands each possess a highly preorganized cavity with an open portal (nearly 1 nm wide), by which guests can enter and egress the cavity. Additionally, these hosts are deep- functionalized with a crown of weakly acidic benzal C [BOND] H groups which can form a variety of noncovalent interactions with guest molecules residing within the cavity. Thirty- ...