High-yield acyl anion trapping reactions: syntheses of. alpha.-hydroxy ketones and 1, 2-diketones

D Seyferth, RM Weinstein…

Index: Seyferth, Dietmar; Weinstein, Robert M.; Wang, Wei-Liang Journal of Organic Chemistry, 1983 , vol. 48, # 7 p. 1144 - 1146

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Citation Number: 39

Abstract

Summary: The in situ generation of n-C4HgC (0) Li by the reaction of n-C4H&i with CO at- 110" C in the presence of ketones gives good (50-90%) yields of a-hydroxy ketones. When the n-C4HgC (0) Li reaction is carried out in the presence of esters, good (65-80%) yields of a-diketones are obtained, thus demonstrating that RC (0) Li can be

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