Highly Enantiospecific Platinum-Catalyzed Cycloisomerizations: Synthesis of Enantioenriched Oxabicycloheptene Derivatives
ET Newcomb, EM Ferreira
Index: Newcomb, Eric T.; Ferreira, Eric M. Organic Letters, 2013 , vol. 15, # 7 p. 1772 - 1775
Full Text: HTML
Citation Number: 12
Abstract
Enantiospecific cycloisomerizations of 1, 6-enynes to form oxabicyclo [4.1. 0] heptene derivatives are described. Enantiospecificity is consistently high regardless of alkene or alkyne substitution, providing a general approach to greatly enantioenriched cyclopropanes. Additionally, a model for stereochemical transfer is proposed.
Related Articles:
[Lu, Gui; Li, Xingshu; Chen, Gang; Chan, Wing Lai; Chan, Albert S. C. Tetrahedron Asymmetry, 2003 , vol. 14, # 4 p. 449 - 452]
Zn (ODf) 2: preparation and application in asymmetric alkynylation of aldehydes
[Chen, Zili; Xiong, Wennan; Jiang, Biao Chemical Communications, 2002 , # 18 p. 2098 - 2099]