Reactivity of α??acylated β??enamino ketones and esters: Synthesis of pyrazoles

…, HS Braibante, MEF Braibante

Index: Missio, Lauri J.; Braibante, Hugo S.; Braibante, Mara E. F. Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 4 p. 1243 - 1245

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Citation Number: 13

Abstract

Abstract The reactivity of the enamino compounds 4-amino-3-phenylamino (thio) carbonyl-3- penten-2-one 1 and 2 and ethyl 3-amino-2-phenylamino (thio) carbonyl-2-butyrate 7 and 8 was studied using the reaction with hydrazine hydrate and hydrazine hydrochloride to evaluate the 1, 3 electrophilic center of the compounds by the formation of the pyrazole rings. The pyrazoles 3, 4, 5, 9, 11 and 13 were obtained depending on the reaction ...