Structure and properties of a stable isoindole. The dimethyl acetylenedicarboxylate-1-(ethylthio)-2-propylisoindole substitution product

…, HL Ammon, R Doherty, DF Johnson

Index: Simons, S. Stoney; Ammon, Herman L.; Doherty, Ruth; Johnson, David F. Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4739 - 4744

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Citation Number: 16

Abstract

1 2, R= alkyl; R'= alkyl, aryl 3, R= n-propyl; R'= CH, CH, OH 4, R= n-propyl; R'= ethyl than other monoheterosubstituted isoindoles21-24 and yield'H NMR spectra which show enough deshielding of substituent methylene groups to indicate substantial aromatic ring current in the isoindole molecule. 23 These isoindoles were previously reported to react with dimethyl acetylenedicarboxylate (DMAC) in a manner more typical of pyrroles than isoindoles. 20 ...