Antiparasitic agents. 6. Synthesis and anthelmintic activities of novel isothiocyanatophenyl-1, 2, 4-oxadiazoles

RD Haugwitz, AJ Martinez, J Venslavsky…

Index: Haugwitz, R. D.; Martinez, A. J.; Venslavsky, J.; Angel, R. G.; Maurer, B. V.; et al. Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1234 - 1241

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Citation Number: 29

Abstract

The syntheses and anthelmintic activities of 31 3-and 5-(isothiocyanatophenyl)-l, 2, 4- oxadiazoles are reported. In the primary anthelmintic screen, 3-(4-isothiocyanatophenyl)-1, 2, 4-oxadiazole(39) showed 100% nematocidal activity and 3-(2-furanyl)-5-(4- ...