3-haloquinolines by friedlander reaction of α-haloketones
SV Ryabukhin, VS Naumchik, AS Plaskon…
Index: Ryabukhin, Sergey V.; Naumchik, Vasiliy S.; Plaskon, Andrey S.; Grygorenko, Oleksandr O.; Tolmachev, Andrey A. Journal of Organic Chemistry, 2011 , vol. 76, # 14 p. 5774 - 5781
Full Text: HTML
Citation Number: 30
Abstract
A general approach to 3-fluoro-, 3-chloro-, and 3-bromoquinolines which relies on organosilane-promoted Friedländer reaction of α-haloketones is described. The scope of the methylene component as well as influence of the organosilane component on the outcome of the reaction is studied. The method can be used under parallel synthesis conditions.
Related Articles:
Reaction of Electrogenerated Dichlorocarbene with Methylindoles
[Angelis, Francesco De; Inesi, Achille; Feroci, Marta; Nicoletti, Rosario Journal of Organic Chemistry, 1995 , vol. 60, # 2 p. 445 - 447]
Reaction of Electrogenerated Dichlorocarbene with Methylindoles
[Angelis, Francesco De; Inesi, Achille; Feroci, Marta; Nicoletti, Rosario Journal of Organic Chemistry, 1995 , vol. 60, # 2 p. 445 - 447]
Reaction of Electrogenerated Dichlorocarbene with Methylindoles
[Angelis, Francesco De; Inesi, Achille; Feroci, Marta; Nicoletti, Rosario Journal of Organic Chemistry, 1995 , vol. 60, # 2 p. 445 - 447]
Body-mass index and mortality in a prospective cohort of US adults
[Joshi, Krishna C.; Jain, Renuka; Arora, Seema Journal of the Indian Chemical Society, 1993 , vol. 70, # 6 p. 567 - 568]
The reaction between 2, 3-dialkylindoles and dichlorocarbene
[Botta, M.; Angelis, F. De; Gambacorta, A. Tetrahedron, 1982 , vol. 38, # 15 p. 2315 - 2318]