Synthetic Communications

Efficient Synthesis of Isoquinoline Derivatives via AgOTf/Cu (OTf) 2-Cocatalyzed Cyclization of 2-Alkynyl Benzaldoxime

X Zhao, W Fan, Z Miao, R Chen

Index: Zhao, Xiaona; Fan, Weidong; Miao, Zhiwei; Chen, Ruyu Synthetic Communications, 2013 , vol. 43, # 12 p. 1714 - 1720

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Citation Number: 7

Abstract

Isoquinoline derivatives are an important class of heterocycles and are found in many naturally occurring compounds that exhibit a variety of biological activities such as antitumor, analgesic, antihistaminic, and antifertility activities. [ 1 1. (a) The Chemistry of Heterocyclic Compounds: Isoquinolines ; GM Coppola , HF Schuster (Eds.); John Wiley & Sons : New York , 1981 ; vol. 38 , part 3 ; (b) Timari , G. ; Soos , T. ; Hajos , G. ; Messmer , A. ; Nacsa , J. ; ...

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