Synthesis of N-vinylpyrroles from N-(2-hydroxyethyl) pyrroles

BF Kukharev, VK Stankevich, VA Kukhareva

Index: Kukharev; Stankevich; Kukhareva Russian Journal of Organic Chemistry, 2011 , vol. 47, # 4 p. 614 - 615

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Abstract

N-Vinylpyrrole derivatives exhibit versatile biological activity and are promising as monomers and intermediate products in the synthesis of a number of compounds possessing practically important properties [1, 2]. In the recent time, the most convenient method for the preparation of these compounds is based on reaction of ketone oximes with acetylene in the system dimethyl sulfoxide–alkali metal hydroxide (Trofimov reaction)[1, 2]. ...