Journal of the American Chemical Society

Novel heterocycles comprised of alternating phosphorous atoms and alkyne units

LT Scott, M Unno

Index: Scott, Lawrence T.; Unno, Masafumi Journal of the American Chemical Society, 1990 , vol. 112, # 21 p. 7823 - 7825

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Citation Number: 38

Abstract

Double deprotonation of 7 (2.2 equiv of EtMgBr, THF, 50 OC, 30 min) followed by slow addition to 1.5 molar equiv of tertbutylphosphonous dichloride (5, THF,-10 OC, then room temperature for 3 h) produced the nine-membered-ring heterocycle 3 in 16% isolated yielda6 The 12-membered-ring heterocycle 4 was likewise prepared in 11% isolated yield by double deprotonation of 6 followed by slow addition to 1.2 molar equiv of ...

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