Synlett

Synthesis of 2-and 3-substituted N-methylpyrroles

E Dvornikova, K KamieŇska-Trela

Index: Dvornikova, Elena; Kamienska-Trela, Krystyna Synlett, 2002 , # 7 p. 1152 - 1154

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Citation Number: 6

Abstract

Abstract A reliable method of synthesis of 3-bromo-N-methylpyrrole by the use of N- bromosuccinimide and a catalytic amount of PBr 3 is reported. The method described opens a facile route to a variety of 3-substituted pyrroles, which are otherwise difficult to access. In addition, conditions under which pure 2-bromo-N-methylpyrrole can be obtained have been established.