DNA Hydrolysis Catalyzed by Tris (diisopropyl??1, 4, 7??triazacyclononanes) ethane Metal Complexes

CC Cheng, YC Huang, MC Liu

Index: Cheng, Chien-Chung; Huang, Yan-Chen; Liu, Ming-Chan Journal of the Chinese Chemical Society, 2004 , vol. 51, # 5 B p. 1201 - 1208

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Abstract

Abstract Novel trinuclear coordinated ligands were designed using three of 1, 4, 7- triazacyclononane moieties with a tribromo linker. These ligands show greater capability and potency in association with various metal ions. Tris (diisopropyl-1, 4, 7- triazacyclononanes) ethane (2) associated with Cu 2+ and Ce 4+ ions shows better reactivity to achieve DNA hydrolysis at 37 C at pH 8 for 5 hr. Using high resolution of ...

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