Tetrahedron Letters

Palladium-catalyzed carboxylative cyclization of α-allenyl amines in dense carbon dioxide

Y Kayaki, N Mori, T Ikariya

Index: Kayaki, Yoshihito; Mori, Naoko; Ikariya, Takao Tetrahedron Letters, 2009 , vol. 50, # 47 p. 6491 - 6493

Full Text: HTML

Citation Number: 25

Abstract

Carboxylative transformation of 2, 3-allenic amines into 5-vinyl-1, 3-oxazolidin-2-ones was promoted by palladium catalysts under a pressurized CO2 condition. The presence of a stereogenic center adjacent to the allene group resulted in the formation of the corresponding cyclic urethane as a single trans-diastereomer.