Cyclization of 2-(4'-Carbomethoxy-2'-oxobutyl)-2-carbomethoxycyclohexanone1a
WL Meyer, BS Bielaski
Index: Meyer,W.L.; Bielaski,B.S. Journal of Organic Chemistry, 1963 , vol. 28, p. 2896 - 2897
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Citation Number: 2
Abstract
Systems like 2-(4'-carbomethoxy-2'-oxobutyl)-2-car-bomethoxycyclohexanone (I) can in principle undergo intramolecular aldol cyclization involving either the C-3'(a to the ketone, path A) or the C-4'(a to the ester, path B) methylene group. Since enolages are normally more readily generated from ketones than from esters one might well expect the former course, leading to the 2-hydrindenone derivative 11, to be favored in a ratecontrolled ...
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