Tetrahedron Letters

A general route to unsubstituted N-aryl and heteroarylaminobenzenesulfonamides

F Lach, MJ Pasquet, M Chabanne

Index: Lach, Franck; Pasquet, Marie-Jeanne; Chabanne, Mylene Tetrahedron Letters, 2011 , vol. 52, # 16 p. 1882 - 1887

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Citation Number: 5

Abstract

Starting from suitably protected 3-and 4-aminobenzenesulfonamides, a practical two-step strategy for the synthesis of unsubstituted N-aryl and heteroarylaminobenzenesulfonamides was devised. Strong bases are tolerated during the N-arylation step. Overall moderate to excellent yields are reported.