Synthesis of new pyrazolo [4, 3??c] quinolin??3??one derivatives and some oxazolo [4, 5??c] quinoline??2, 4??diones

L Ismaili, B Refouvelet, JF Robert

Index: Ismaili, Lhassane; Refouvelet, Bernard; Robert, Jean Francois Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 719 - 722

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Citation Number: 11

Abstract

Abstract The new pyrazolo [4, 3-c] quinolin-3-one derivatives 3a-c and 6a-c were prepared by the following three steps: first the preparation of ethyl 4-hydroxyquinoline-3-carboxylate derivatives 1 and 4 by reaction of isatoic anhydrides and ethyl malonate and ethyl acetoacetate respectively, then chloration of 1 and 4 with phosphorus oxychloride to give 2 and 5 and finally the condensation of 2 and 5 with hydrazine and its derivatives. In ...

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