Synthesis and antiviral activity of pyrazolo [3, 4-d]-1, 3, 2-diazaphosphorins

…, NP Solov'eva, IS Nikolaeva, VV Peters…

Index: Nilov; Solov'eva; Nikolaeva; Peters; Krylova; Gus'kova; Granik Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 7 p. 358 - 361

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Citation Number: 11

Abstract

The interaction between compounds containing amino and carbamoyl (or thiocarbamoyl) groups in the neighboring positions, on the one hand, and the P2S5-pyridine system, on the other hand, may readily close the 1, 3, 2Miazaphosphorin cycle [1-4]. This approach was used for the synthesis of phosphorus-containing analogs of purines [3] and pyrimidines [4]. The group of pyrazolo-[3, 4-d] pyrimidine derivatives was reported to include compounds ...