Hydrogenation of 1, 3-Diketones to Ketols

PS Stutsman, H Adkins

Index: Stutsman; Adkins Journal of the American Chemical Society, 1939 , vol. 61, p. 3306

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Citation Number: 12

Abstract

Spraguel obtained the ketol (CH3) 3CC (0) CH2-CHOHCH3 in 68% yield by the hydrogenation of (CH3), CC (0) CH2C (O) CH3. This rather unexpected result was no doubt due to the relative resistance to hydrogenation of a carbonyl group adjacent to a tertiary butyl group. The study reported herewith was directed toward finding conditions under which other ketols, less resistant to hydrogenation, could be obtained by the partial ...