Solid-Liquid Phase Transfer Catalysis Without Solvent: A Mild and Efficient Preparation of Mono and Di-Ethers Derived from 8-Hydroxyquinoline

…, A Loupy, J Sansoulet, H Strzelecka

Index: Bram, G.; Loupy, A.; Sansoulet, J.; Strzelecka, H. Synthetic Communications, 1984 , vol. 14, # 9 p. 889 - 898

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Citation Number: 10

Abstract

Abstract The title compounds are easily prepared by reaction of 8-hydro-xyquinoline with either 1 eq. CnH2n+ 1Br (2≤ n≤ l6) or 0.5 eq. Br (CH2) nBr (3≤ n≤ 6) in the presence of 1 eq. finely ground KOH and 2% Aliquat 336. Reactions are performed in the absence of any organic solvent. Yields and experimental conditions compare very favourably to those obtained previously by classical methods.