De novo synthesis and lectin binding studies of unsaturated carba-pyranoses

T Leermann, O Block, MAL Podeschwa…

Index: Leermann, Timo; Block, Oliver; Podeschwa, Michael A. L.; Pfueller, Uwe; Altenbach, Hans-Josef Organic and Biomolecular Chemistry, 2010 , vol. 8, # 17 p. 3965 - 3974

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Citation Number: 5

Abstract

Starting from branched para-benzoquinones a practical and highly flexible route is described for the preparation of unsaturated carbapyranoses. The potential of the synthesized galactose analogues to act as competitive inhibitors in lectin-carbohydrate interactions is investigated by means of Surface Plasmon Resonance (SPR) Spectroscopy.